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Research

Outcome Study ONTARGET

1 Apr 2008

ONTARGET results have been released- click here.

A large, simple, randomized, double-blind, ... › More

A Study of the Effect on Pain Control of Treatment With Fentanyl, Administered Through the Skin, in Patients With Rheumatoid Arthritis or Osteoarthritis

8 Nov 2007
The purpose of this study is to assess the degree of pain control achieved by treatment with fentanyl, administered via adhesive patches applied to the skin ('transdermal system') in patients with ... › More

BMS-354825 in Patients With Chronic Accelerated, or Blast Phase Chronic Myelogenous Leukemia or Philadelphia Positive Acute Lymphoblastic Leukemia

30 Oct 2007
The purpose of this clinical research study is to understand the safety and efficacy of BMS-354825 in patients with chronic, accelerated, or blast phase chronic myelogenous leukemia (CML) or ... › More

Bortezomib in Treating Patients With Newly Diagnosed High-Risk Stage III Multiple Myeloma

22 Oct 2007
RATIONALE: Bortezomib may stop the growth of cancer cells by blocking the enzymes necessary for their growth. PURPOSE: This phase II trial is studying how well bortezomib works in treating patients ... › More

Effect of Pantoprazole on the Symptoms of Acid Reflux Disease in Adult Patients (BY1023/M3-341)

12 Oct 2007
The aim of the present study is to identify factors (such as symptom patterns and symptom scores) that influence the response to treatment with pantoprazole using different evaluation methods (e.g. ... › More

Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer

9 Oct 2007
Randomized phase III trial to compare the effectiveness of cisplatin plus gemcitabine with or without paclitaxel in treating patients who have stage IV urinary tract cancer. › More

A Study to Determine the Long-Term Efficacy and Safety of Ramelteon in Adults With Chronic Insomnia.

3 Aug 2007
The study will involve an evaluation of the efficacy and safety of ramelteon (TAK-375) over a 6-month period in adults and elderly subjects with chronic insomnia. The test agent ramelteon will be ... › More

PROMPT Clinical Trial for Migraine Prevention

23 Jul 2007
Various national and local guidelines demand revision of migraine prevention therapy after 4 to 6 months of treatment. However, there is no evidence from clinical studies to support the validity of ... › More

Efficacy and Safety of Zoledronic Acid for the Treatment of Osteoporosis in Men

5 Jul 2007
The goal of this study is to determine the effectiveness and safety of an annual intravenous treatment of zoledronic acid for the treatment of osteoporosis in men. All patients will receive calcium ... › More

Menevit Study: Menevit Anti-Oxidant Therapy for the Treatment of Male Infertility

20 Jun 2007
Oxidative stress related damage to sperm is believed to be a major cause of male infertility. The object of the Menevit study is to investigate the role of a novel anti-oxidant preparation (Menevit) ... › More

Trials

FIELD -Fenofibrate Intervention and Event Lowering in Diabetes

12 Nov 2007
The FIELD trial "Fenofibrate Intervention and Event Lowering in Diabetes" aims to determine whether treatment with fenofibrate, a potent modifier of blood lipid levels, will reduce the risk of fatal ... › More

EMPOWER Clinical Trial: Vagal Blocking for Obesity Control

26 Aug 2007
This is a randomized multi-center study being done to measure the ability of a new medical device, Maestro System, to safely reduce body weight over five years in people who are considered obese. › More

Efficacy and Safety Study of Combined Oral and Injection Therapy for Erectile Dysfunction

27 Jul 2007
Aim of the study is to test the safety and efficacy of a combination of Viagra and Caverjet Impulse in a group of men who had failed to achieve an adequate response to the maximum recommended dose of ... › More

Methods Study to Characterize Early Indicators of Weight Loss in People.

20 Jul 2007
This study will measure the changes that indicate successful weight loss in people. › More

Study The Effects Of Different Doses Of UK-369,003 In Men With Overactive Bladder.

16 Jun 2007
This is a 12 week study in which different doses of UK-369,003 will be administered to patients with a diagnosis of overactive bladder. Patients will complete a series of questionnaires before ... › More

PI-88 and/or Dacarbazine in Treating Patients With Metastatic Melanoma That Cannot Be Removed By Surgery

15 Jun 2007
PI-88 may stop the growth of tumour cells by blocking blood flow to the tumour. Drugs used in chemotherapy, such as dacarbazine, work in different ways to stop the growth of tumour cells, either by ... › More

A Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-583 in Subjects With Postherpetic Neuralgia (PHN)

31 May 2007
The purpose of the study is to assess the safety and ability of TAK-583 to relieve pain in subjects with PHN, compared with placebo. › More

Sympathetic Activity in Individuals With the Metabolic Syndrome: Benefits of Lifestyle Interventions

31 May 2007
An abdominal distribution of fat is associated with the greatest heart disease risk, because commonly, several risk factors of metabolic origin (high blood pressure, unfavourable cholesterol profile, ... › More

Antiviral Activity of Entecavir in Patients Receiving Liver Transplant Due to Chronic Hepatitis B Virus Infection

17 May 2007
The purpose of this clinical research study is to learn if the study drug entecavir will prevent the recurrence of hepatitis B virus in subjects who receive an orthotopic liver transplant (OLT). › More

A Study of the Effectiveness of Virtual Reality Relaxation Combined With Patient-Controlled Analgesia (PCA) Morphine for Those Undergoing Burn Dressing Changes

14 May 2007
The purpose of this study is to evaluate whether a sub-population of patients with burn injuries needing dressing changes respond to virtual reality (VR) utilising relaxation themes with improved ... › More

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